Thora Birch

Enid

Scarlett Johansson

Rebecca

Steve Buscemi

Seymour

Brad Renfro

Josh

Illeana Douglas

Roberta Allsworth

Bob Balaban

Enid's Dad

Stacey Travis

Dana

Charles C. Stevenson Jr.

Norman

Dave Sheridan

Doug

Tom McGowan

Joe

Debra Azar

Melora

Brian George

Sidewinder Boss

Pat Healy

John Ellis

Rini Bell

Graduation Speaker

T.J. Thyne

Todd

Ezra Buzzington

Weird Al

Lindsey Girardot

Vanilla

Joy Bisco

Jade

Venus DeMilo Thomas

Ebony

Ashley Peldon

Margaret

Marc Vann

Angry Guy (Jerome)

James Sie

Asian Guy (Steven)

Paul Keith

Fussy Guy (Paul)

David Cross

Pushy Guy (Gerrold)

Dylan Jones

Red-Haired Girl

Martin Grey

M.C.

Jake La Botz

Blueshammer Member

Charles Schneider

Joey McCobb

Sid Hillman

Zine-O-Phobia Creep

Patrick Fischler

Masterpiece Video Clerk

Daniel Graves

Masterpiece Video Customer

Matt Doherty

Masterpiece Video Employee

Debi Derryberry

Rude Coffee Customer

Joseph Sikora

Reggae Fan

Alex Solowitz

Cineplex Manager

Brian Jacobs

Soda Customer

Lauren Bowles

Angry Garage Sale Woman

Lorna Scott

Phyllis, the Art Show Curator

Jerry Rector

Dana's Co-Worker

Diane Salinger

Psychiatrist

Anna Berger

Seymour's Mother

Bruce Glover

Feldman (Wheelchair Guy)

Teri Garr

Maxine (uncredited)

Joan Blair

Lady Slowly Crossing Street (uncredited)

Michelle McGinty

Mom in Convenience Store (uncredited)

Will Forte

(uncredited)