Gary Cooper

Henry Louis 'Lou' Gehrig

Teresa Wright

Eleanor Twitchell

Babe Ruth

Babe Ruth

Walter Brennan

Sam Blake

Dan Duryea

Hank Hanneman

Elsa Janssen

Christina 'Mom' Gehrig

Ludwig Stössel

Henry 'Pop' Gehrig

Virginia Gilmore

Myra Tinsley

Bill Dickey

Bill Dickey

Ernie Adams

Miller Huggins

Pierre Watkin

Mr. Twitchell

Harry Harvey

Joe McCarthy

Addison Richards

Coach

Hardie Albright

Van Tuyl

Edward Fielding

Clinic Doctor

George Lessey

Mayor of New Rochelle

Edgar Barrier

Hospital Doctor

Douglas Croft

Lou Gehrig as a Boy

David Holt

Billy (Age 17)

Veloz

Specialty Dancer (as Veloz and Yolanda)

Yolanda

Specialty Dancer (as Veloz and Yolanda)

Hooper Atchley

Lathered Man in Barber Shop (uncredited)

Edwin August

Restaurant Patron (uncredited)

Lynton Brent

Photographer in Hospital (uncredited)

Betty Brewer

Little Girl (uncredited)

Don Brodie

Girl Show Barker (uncredited)

Charles Cane

Plumber (uncredited)

Eddy Chandler

Motorcycle Cop #2 (uncredited)

Lane Chandler

Mark - Player in Locker Room (uncredited)

Janet Chapman

Tessie (uncredited)

Spencer Charters

Mr. Larsen (uncredited)

Dane Clark

Fraternity Boy (uncredited)

Heinie Conklin

Wallpaper Hanger (uncredited)

Clancy Cooper

Motorcycle Cop #1 (uncredited)

John Daheim

Reporter in Hospital (uncredited)

Lester Dorr

Disappointed Fan #1 (uncredited)

Frank Faylen

Yankee Third Base Coach (uncredited)

Walter Fenner

Dentist (uncredited)

Pat Flaherty

Yankee Ballplayer (uncredited)

Rosina Galli

Mrs. Fabrini (uncredited)

Vaughan Glaser

Doctor in Gehrig Home (uncredited)

Mary Gordon

Maid (uncredited)

George Guhl

Second Paper Hanger (uncredited)

Eddie Hall

Reporter in Hospital Room (uncredited)

Harry Hayden

Department Store Manager (uncredited)

Vinton Hayworth

Fraternity Boy (uncredited)

Earle Hodgins

Bottle Game Operator (uncredited)

Fay Holderness

Spectator (uncredited)

John Ince

Man in Box Seat (uncredited)

Mitchell Ingraham

Barber (uncredited)

John Kellogg

Fraternity Boy (uncredited)

Colin Kenny

Yankee Player on Train (uncredited)

Donald Kerr

Photographer (uncredited)

Rex Lease

Spectator (uncredited)

Theodore Lorch

Neighbor Leaning Through Window (uncredited)

Wilbur Mack

Man Outside Yankee Stadium (uncredited)

Matt McHugh

Strength Machine Operator (uncredited)

Wilmuth Merkyl

Spectator (uncredited)

Howard M. Mitchell

Sportsman at Ballgame (uncredited)

Tom Neal

Fraternity Boy (uncredited)

Ray Noble

Orchestra Leader (uncredited)

Patsy O'Byrne

Scrubwoman (uncredited)

George Offerman, Jr.

Freshman (uncredited)

Garry Owen

Scorecard Vendor (uncredited)

Sarah Padden

Mrs. Roberts (uncredited)

Emory Parnell

Chicago Policeman O'Doul (uncredited)

Edward Peil Sr.

Policeman (uncredited)

Cyril Ring

Photographer (uncredited)

Art Rowlands

Telephone Man (uncredited)

William Roy

Joe Fabrini (uncredited)

Anita Sharp-Bolster

Sasha's Mother (uncredited)

C. Montague Shaw

Mr. Worthington (uncredited)

John Sheehan

First Paper Hanger (uncredited)

Jack Stewart

Ed Barrow (uncredited)

Ben Taggart

Conductor (uncredited)

Walter Tetley

Cake Delivery Boy (uncredited)

Dorothy Vaughan

Eleanor's Landlady (uncredited)

Dorothy Vernon

Family Friend (uncredited)

Malcolm Waite

Big Strength Machine Contestant (uncredited)

James Westerfield

Spectator (uncredited)

Guy Wilkerson

Sportsman at Ballgame (uncredited)

Charles Williams

Little Strength Machine Contestant (uncredited)