Zac Efron

Jim Carrico

Marcia Gay Harden

Doris Nelson

Paul Giamatti

Abraham Zapruder

Billy Bob Thornton

Forrest Sorrels

Jacki Weaver

Marguerite Oswald

Ron Livingston

James Hosty

Jeremy Strong

Lee Harvey Oswald

James Badge Dale

Robert Oswald

Tom Welling

Roy Kellerman

Colin Hanks

Dr. Malcom Perry

Jackie Earle Haley

Father Oscar Huber

David Harbour

Gordon Shanklin

Paul Sparks

Harry McCormick

Mark Duplass

Kenneth O'Donnell

Rory Cochrane

Earl Rose

Matt Barr

Paul Mikkelson

Austin Nichols

Emory Roberts

Gil Bellows

David Powers

Jonathan Breck

Winston Lawson

Elizabeth Tulloch

Marilyn Sitzman

Dana Wheeler-Nicholson

Lillian Zapruder

Kat Steffens

Jacqueline Kennedy

Brett Stimely

President Kennedy

Sean McGraw

Lyndon B. Johnson

Jimmie Dale Gilmore

Reverend Saunders

Gary Grubbs

Dr. Kemp Clark

Bryan Batt

Malcolm Kilduff

Glenn Morshower

Mike Howard

Chuck Huber

Hugh Jamieson

Gary Clarke

Admiral George Burkley

Mallory Moye

Emergency Room Nurse

Jason Douglas

Ken Howe

Larry Jack Dotson

Acme Brick Supervisor

Nico Evers-Swindell

Rufus Youngblood

Irene White

Hospital Switchboard Operator #1

Luci Christian

Hospital Switchboard Operator #2

Chris Freihofer

Chamberlain

Taylor Joree Scorse

Nurse

Oryan Landa

Texas Ranger

Heath Allyn

Secret Service Agent (uncredited)

John Cann

Secret Service Agent (uncredited)

Anthony J. Caruso

Secret Service Agent (uncredited)

Darryl Cox

Gen. Godfrey McHugh (uncredited)

Anne Lockhart

ER Nurse (uncredited)

Greg Wise

Doctor in Trauma Room (uncredited)

Armando Gutierrez

Dallas Police Officer - Glen McBride (uncredited)

Eugene Lee

Orderly

Samuel Davis

Trauma Resident

Matthew Tompkins

Secret Service Agent

Chamblee Ferguson

Dallas Morning News Lab Tech

Rob Gallavan

Lem Johns

Robert Catrini

Funeral Director

Richard Dillard

Theron Ward

Richard Jackson

Sgt. Bob Dugger

Jeffrey Schmidt

Richard Stolley

Peggy Schott

Nellie Connally (uncredited)