Matthew Modine

Dr. Don Francis

Alan Alda

Dr. Robert Gallo

Patrick Bauchau

Dr. Luc Montagnier

Nathalie Baye

Dr. Françoise Barre

Christian Clemenson

Dr. Dale Lawrence

David Clennon

Mr. Johnstone

Phil Collins

Eddi Papasano

Bud Cort

Antique Shop Owner

Alex Courtney

Dr. Mika Popovic

David Dukes

Dr. Mervyn Silverman

Richard Gere

The Choreographer

David Marshall Grant

Dennis Seeley

Ronald Guttman

Dr. Jean-Claude Chermann

Glenne Headly

Dr. Mary Guinan

Anjelica Huston

Dr. Betsy Reisz

Ken Jenkins

Dr. Dennis Donohue

Richard Jenkins

Dr. Marc Conant

Tchéky Karyo

Dr. Willy Rozenbaum

Swoosie Kurtz

Mrs. Johnstone

Jack Laufer

Mrs. Johnstone

Donal Logue

Bobbi Campbell

Steve Martin

The Brother

Richard Masur

William W. Darrow, PhD

Dakin Matthews

Congressman Phil Burton

Ian McKellen

Bill Kraus

Peter McRobbie

Dr. Max Essex

Lawrence Monoson

Chip

Jeffrey Nordling

Gaetan Dugas

Saul Rubinek

Dr. Jim Curran

Charles Martin Smith

Dr. Harold Jaffe

Stephen Spinella

Brandy Alexander

Lily Tomlin

Dr. Selma Dritz

BD Wong

Kico Govantes

Walter Addison

Blood Bank Executive

Jill Andre

Red Cross Spokesperson

David Dean Bottrell

Man #3

Rico Bueno

Bellevue Hospital Patient

Christopher Carroll

Dr. Aaron Kellner

Reg E. Cathey

Staff Doctor #2

John Durbin

6th Man

Mogens Eckert

Chief Executive (Copenhagen)

Carey Eidel

Tennis Player

Robert Briscoe Evans

2nd Reporter

Richard Fancy

Dr. Michael Gottlieb

Keythe Farley

Lab Technician

Christopher John Fields

Lawyer

Dave Florek

Doughnut Shop Counterman

Yasmine Golchan

Dr. Françoise Brun-Vezinet

Patrick Gorman

Charles Dauget

James Greene

Dr. Alvin Freedman-Kien

Jeff Hayenga

Dr. Bruce Voeller

Laura Innes

Hemophiliac Representative

Michael Kearns

Cleve

Jack Kenny

San Francisco Activist

Thomas Kopache

Blood Bank Executive

Clyde Kusatsu

Blood Bank Executive

Rob LaBelle

Gay Rights Activist

Neal Lerner

1st Man

René Le Vant

Blood Bank Executive

Rosemary Murphy

Blood Bank Executive

Angela Paton

Woman in Denver

Sierra Pecheur

Female Reporter

Miguel Pérez

Reporter

Valeri Ross

Jim's Secretary

Tom Schanley

Waiter

Michael Winters

Middle-Aged Man

Lenny Wolpe

Dr. Joseph Bove

Geoffrey Lower

Dr. David Simpson (as Geoff Lower)