Steve Carell

Gru / Dru (voice)

Kristen Wiig

Lucy Wilde (voice)

Trey Parker

Balthazar Bratt (voice)

Miranda Cosgrove

Margo (voice)

Dana Gaier

Edith (voice)

Nev Scharrel

Agnes (voice)

Steve Coogan

Fritz / Silas Ramsbottom (voice)

Julie Andrews

Gru’s Mom (voice)

Jenny Slate

Valerie Da Vinci (voice)

Pierre Coffin

Mel / Minions / Museum Director / Additional Voices (voice)

Chris Renaud

Additional Minions (voice)

Andy Nyman

Clive the Robot (voice)

Michael Beattie

The Scar Faced Man / TMZ Announcer (voice)

Adrian Ciscato

Niko (voice)

Brian T. Delaney

Commercial Announcer / Military Officer / Additional Voice (voice)

Ken Daurio

Celebrity (voice)

Lori Alan

Additional Voices (voice)

Carlos Alazraqui

Additional Voices (voice)

Kyle Balda

Additional Voices (voice)

Teresa Ganzel

Additional Voices (voice)

Bob Bergen

Additional Voices (voice)

Jess Harnell

Additional Voices (voice)

Gregg Berger

Additional Voice (voice)

John Kassir

Additional Voice (voice)

Mona Marshall

Additional Voice (voice)

John Cygan

Additional Voice (voice)

Laraine Newman

Additional Voice (voice)

Jan Rabson

Additional Voices (voice)

Bill Farmer

Additional Voices (voice)

Mindy Sterling

Additional Voice (voice)

Danny Mann

Additional Voices (voice)

Jim Ward

Additional Voice (voice)

Matthew Wood

Additional Voice (voice) (uncredited)

Cory Walls

Vincenzo (voice)

Gregg Berger

Additional Voices (voice)

Tara Strong

Additional Voices (voice)