Steve Carell

Gru / Dru (voice)

Kristen Wiig

Lucy Wilde (voice)

Trey Parker

Balthazar Bratt (voice)

Miranda Cosgrove

Margo (voice)

Dana Gaier

Edith (voice)

Nhev Scharrel

Agnes (voice)

Pierre Coffin

Mel / Minions / Museum Director / Additional Voices (voice)

Steve Coogan

Fritz / Silas Ramsbottom (voice)

Julie Andrews

Gru’s Mom (voice)

Jenny Slate

Valerie Da Vinci (voice)

Michael Beattie

Scar-Faced Man / TMZ Announcer (voice)

Andy Nyman

Clive the Robot (voice)

Adrian Ciscato

Niko (voice)

Brian T. Delaney

Commercial Announcer / Military Officer / Additional Voice (voice)

Ken Daurio

Celebrity (voice)

Cory Walls

Vincenzo (voice)

Lori Alan

Additional Voices (voice)

Carlos Alazraqui

Additional Voices (voice)

Kyle Balda

Additional Voices (voice)

Bob Bergen

Additional Voices (voice)

Gregg Berger

Additional Voice (voice)

John Cygan

Additional Voice (voice)

Bill Farmer

Additional Voices (voice)

Danny Mann

Additional Voices (voice)

Bruno Dequier

Additional Voice (voice)

Teresa Ganzel

Additional Voices (voice)

Jess Harnell

Additional Voices (voice)

John Kassir

Additional Voice (voice)

Mona Marshall

Additional Voice (voice)

Laraine Newman

Additional Voice (voice)

Jan Rabson

Additional Voices (voice)

Mindy Sterling

Additional Voice (voice)

Tara Strong

Additional Voices (voice)

Jim Ward

Additional Voice (voice)

Gregg Berger

Additional Voices (voice)

Chris Renaud

Additional Minions (voice) (uncredited)

Matthew Wood

Additional Voice (voice) (uncredited)