While investigating the furtive world of illegal doping in sports, director Bryan Fogel connects with renegade Russian scientist Dr. Grigory Rodchenkov—a pillar of his country's "anti-doping" program. Over dozens of Skype calls, urine samples, and badly administered hormone injections, Fogel and Rodchenkov grow closer despite shocking allegations that place Rodchenkov at the center of Russia's state-sponsored Olympic doping program.