Dwayne Johnson

Dr. Smolder Bravestone

Kevin Hart

Franklin 'Mouse' Finbar

Jack Black

Professor Sheldon 'Shelly' Oberon

Karen Gillan

Ruby Roundhouse

Awkwafina

Ming

Nick Jonas

Jefferson 'Seaplane' McDonough

Alex Wolff

Spencer Gilpin

Morgan Turner

Martha Kaply

Madison Iseman

Bethany

Ser'Darius Blain

Anthony 'Fridge' Johnson

Danny DeVito

Eddie

Danny Glover

Milo

Rhys Darby

Nigel Billingsley

Colin Hanks

Alex

Rory McCann

Jurgen the Brutal

Marin Hinkle

Spencer's Mom

Vince Pisani

Pharmacy Manager

Dorothy Steel

Village Elder

Jennifer Patino

Bravestone's Mother

Madison Johnson

Little Bethany Vreeke

Dania Ramirez

Lady in Red

Derek Russo

Key Master

Nick Gomez

Oasis Drunk

Massi Furlan

Switchblade

Javier Villamil

Switchblade's Sidekick

Morgan Brown

Fortress Guard

Deobia Oparei

Elevator Guard

Leslie Simms

Cake Lady

John Ross Bowie

Cavendish

Lucy DeVito

Maiden

Bebe Neuwirth

Nora

Lamorne Morris

Heater Repair Guy

Darin Ferraro

The Gun Seller (uncredited)

Sal Longobardo

Tony (uncredited)

Michael Beasley

Coach Davis (uncredited)

Charles Green

Bartender (uncredited)

Kodai Yamaguchi

Jumanjian Villager (uncredited)

Ashley Scott

Ashley (uncredited)

Melissa Kennemore

Marauder 1 / Jergens Inner Circle (uncredited)

Vanessa Cater

Red Headed Marauder (uncredited)

Sheril Rodgers

New York City Pedestrain (uncredited)

Bruno Rose

NY Dorm Guy (uncredited)