Cailey Fleming

Bea

Ryan Reynolds

Cal

John Krasinski

Dad / Marshmallow (voice)

Fiona Shaw

Grandmother

Steve Carell

Blue (voice)

Phoebe Waller-Bridge

Blossom (voice)

Louis Gossett Jr.

Lewis (voice)

Alan Kim

Benjamin

Liza Colón-Zayas

Janet

Bobby Moynihan

Jeremy

Catharine Daddario

Bea’s Mom

Audrey Hoffman

Bea (Ages 3 & 5)

Laquet Sharnell Pringle

Receptionist

Ed Herbstman

Deli Guy

Barbara Andres

Woman Upstairs

Alexander Rivero

Custodian

Shauna Pinkett

Hospital Receptionist

Sa'Raya Paris Johnson

7 Year-Old Girl

David Weissmann

Young Jeremy

Awkwafina

Bubble (voice)

Emily Blunt

Unicorn (voice)

George Clooney

Spaceman (voice)

Bradley Cooper

Ice (voice)

Matt Damon

Flower (voice)

Bill Hader

Banana (voice)

Richard Jenkins

Art Teacher (voice)

Keegan-Michael Key

Slime (voice)

Blake Lively

Octopuss (voice)

Sebastian Maniscalco

Magician Mouse (voice)

Christopher Meloni

Cosmo (voice)

Matthew Rhys

Ghost (voice)

Sam Rockwell

Guardian Dog (voice)

Maya Rudolph

Alligator (voice)

Amy Schumer

Gummy Bear (voice)

Allyson Seeger

Viola (voice)

Jon Stewart

Robot (voice)

Craig 'Radio Man' Castaldo

Radio Man (uncredited)