Eddie Murphy

Rayford Gibson

Martin Lawrence

Claude Banks

Obba Babatundé

Willie Long

Nick Cassavetes

Sergeant Dillard

Anthony Anderson

Cookie

Barry Shabaka Henley

Pokerface

Brent Jennings

Hoppin' Bob

Bernie Mac

Jangle Leg

Miguel A. Núñez Jr.

Biscuit

Michael Taliferro

Goldmouth

Guy Torry

Radio

Bokeem Woodbine

Can't Get Right

Ned Beatty

Dexter Wilkins

Lisa Nicole Carson

Sylvia

O'Neal Compton

Superintendant Abernathy

Noah Emmerich

Stan Blocker

Rick James

Spanky Johnson

Clarence Williams III

Winston Hancock

Heavy D

Jake

Ned Vaughn

Young Sheriff Pike

R. Lee Ermey

Older Sheriff Pike

Sanaa Lathan

Daisy

Poppy Montgomery

Older Mae Rose Abernathy

Walter K. Jordan

Slim

Brooks Almy

Billy's Mama

Hal Havins

Billy

Hildy Brooks

Nurse Doherty

Armelia McQueen

Mrs. Clay

Don Harvey

Man with Lantern

Venus DeMilo Thomas

Juke Joint Waitress

Keith Burke

Shady Cardplayer

Sean Lampkin

Trustee at Line

Haskell V. Anderson III

Junkie (as Haskell Vaughn Anderson III)

Kimble Jemison

Gang Banger

Jordan Mahome

Gang Banger

William S. Taylor

Bagman (as William Taylor)

Oscar Jordan

Juke Joint Guitarist

Jordan Lund

Funeral Chaplain

Betty Murphy

Mrs. Abernathy

Dawn Robinson

Club Crooner

Steve Boyles

Mule Cart Driver

Sydney 'Big Dawg' Colston

Henchman (uncredited)