Katherine Heigl

Jane Nichols

James Marsden

Kevin Doyle

Malin Åkerman

Tess Nichols

Judy Greer

Casey

Edward Burns

George

Melora Hardin

Maureen

Brian Kerwin

Hal Nichols

Maulik Pancholy

Trent

David Castro

Pedro

Krysten Ritter

Gina the Goth

Jennifer Lim

Bridal Salesgirl

Danielle Skraastad

Bride Suzanne

Yetta Gottesman

Hip Bridesmaid

Erin Fogel

Shari Rabinowitz

Bern Cohen

Rabbi

Peyton List

Young Jane

Jane Pfitsch

Cousin Lisa

Ronald Guttman

Antoine

Ron Simons

Boathouse Chef

Robert Clohessy

Dive Bartender

Michael Mosley

Bar Dude

Alyssa Bresnahan

Diner Waitress

Jennifer Bassey

Jane's Aunt

Alexa Havins

Boat Bride

Kathryn Weisbeck

Tara Bride (uncredited)