Benicio del Toro

Ernesto Che Guevara

Carlos Bardem

Moisés Guevara

Demián Bichir

Fidel Castro

Joaquim de Almeida

President René Barrientos

Pablo Durán

Pacho (Alberto Fernández Montes de Oca)

Eduard Fernández

Ciro Algarañaz

Marc-André Grondin

Régis Debray

Óscar Jaenada

Darío (David Ardiazola)

Kahlil Méndez

Urbano (Leonardo Tamayo Núñez)

Cristian Mercado

Inti (Guido Peredo Liegue)

Jordi Mollà

Captain Mario Vargas

Gastón Pauls

Ciro Bustos

Jorge Perugorría

Joaquin (Juan Vitalo 'Vilo' Acuña)

Lou Diamond Phillips

Mario Monje

Franka Potente

Tania (Haydee Tamara Bunke Bider)

Othello Rensoli

Pombo (Harry Villegas Tamayo)

Armando Riesco

Benigno (Dariel Alarcón Ramirez)

Catalina Sandino Moreno

Aleida March

Norman Santiago

Tuma (Carlos Coello)

Rodrigo Santoro

Raúl Castro

Mark Umbers

George Roth

Yul Vazquez

Alejandro Ramírez

Ezequiel Díaz

Loro (Jorge Vázquez Viaña)

Rubén Ochandiano

Rolando (Eliseo Reyes Rodriguez)

Carlos Acosta-Milian

Antonio Domínguez Flores

Óscar Avilés

Pedro (Antonio Jiménez Tardio)

Marisé Álvarez

Vilma Espín

Antonio de la Torre

Lieutenant Carlos Fernández

Luis Bredow

Honorato Rojas

Bart Santana

Daniel (Pastor Barrera Quintana)

Jesús Carrillo

Vicente Roeabado Terrazas

Juan Carlos Vellido

Major Hernán Plata

Raúl Arévalo

Captured Soldier #1

Daniel Holguín

Captured Soldier #2

James D. Dever

Major Ralph 'Pappy' Shelton

Roberto San Martín

Captain Gary Prado

Luis Callejo

Bolivian Interrogator

Matt Damon

Fr. Schwartz

Pedro Casablanc

Colonel Joaquín Zenteno

Tomás del Estal

General Alfredo Ovando Candía

David Selvas

Lieutenant Colonel Andrés Selich

Jesús Carroza

Eduardo

Enrique Arce

Lieutenant Carlos Pérez

Cristhian Esquivel

Sergeant Mario Terán

Mariu Bárcena

Embassy Girl (uncredited)

Uzimann

Indian Diplomat (uncredited)

Steven Weisz

News Cameraman (uncredited)