Tom Cruise

Ethan Hunt

Philip Seymour Hoffman

Owen Davian

Ving Rhames

Luther

Billy Crudup

Musgrave

Michelle Monaghan

Julia

Jonathan Rhys Meyers

Declan

Keri Russell

Lindsey Farris

Maggie Q

Zhen

Simon Pegg

Benji

Eddie Marsan

Brownway

Laurence Fishburne

Theodore Brassel

Bahar Soomekh

Davian's Translator

Jeff Chase

Davian's Bodyguard

Michael Berry Jr.

Julia's Kidnapper

Carla Gallo

Beth

Bellamy Young

Rachael

Paul Keeley

Ken

Jane Daly

Julia's Mother

Greg Grunberg

Kevin

Sabra Williams

Annie

Rose Rollins

Ellie

Sasha Alexander

Melissa

Tracy Middendorf

Ashley

Aaron Paul

Rick

Kathryn Fiore

Party Goer

Colleen Crozier

Party Goer

Sean O'Bryan

Party Goer

Bruce French

Minister

Ellen Bry

Lindsey's Mother

Patrick Pankhurst

Lindsey's Father

Tony Guma

Jim

James Shanklin

Hospital Chaplain

Anne Betancourt

Nurse Sally

Andrea Sartoretti

Roadblock Driver

Antonio Del Prete

Vatican Video Room Guard

Francesco De Vito

Greeting Priest

Giorgio Marchesi

Vatican Gate Guard

Niccolò Senni

Vatican Gate Guard

Paolo Bonacelli

Monsignore

Michael G. Kehoe

Hospital Employee

Timothy Omundson

IMF Agent

José Zúñiga

IMF Agent Pete

William Francis McGuire

IMF Head of Security

Michelle Arthur

Airline Worker

Barney Cheng

Janitor

George Cheung

Shanghai Game Player (uncredited)

Brandon Molale

Torturer (uncredited)

Simon Rhee

Chinese Guard at Hengshan Lu Building (uncredited)

Marcus Young

Chinese Guard (uncredited)

Jerry Trimble

Davian's Thug (uncredited)

Alex Kurtzman

Party Guest (uncredited)

Roberto Orci

Party Guest (uncredited)