Robert De Niro

Rupert Pupkin

Jerry Lewis

Jerry Langford

Diahnne Abbott

Rita

Sandra Bernhard

Masha

Shelley Hack

Cathy Long

Frederick de Cordova

Bert Thomas

Ed Herlihy

Ed Herlihy

Marta Heflin

Young Girl

Catherine Scorsese

Rupert's Mom (voice)

Cathy Scorsese

Dolores

Chuck Low

Man in Chinese Restaurant

Liza Minnelli

Liza Minnelli

Margo Winkler

Receptionist

Mick Jones

Street Scum

Joe Strummer

Street Scum

Paul Simonon

Street Scum

Ellen Foley

Street Scum

Don Letts

Street Scum

Matt Russo

Cabbie

Joyce Brothers

Dr. Joyce Brothers

Victor Borge

Victor Borge

Ralph Monaco

Raymond Wirtz

Kim Chan

Jonno

Jay Julien

Langford's Lawyer

Bill Minkin

McCabe

Tony Devon

Plainclothesman

Martin Scorsese

TV Director

Tony Randall

Tony Randall

Charles Scorsese

First Man at Bar

Mardik Martin

Second Man at Bar

Mary Elizabeth Mastrantonio

Crowd Extra (uncredited)