James Stewart

Tom Destry Jr.

Marlene Dietrich

Frenchy

Mischa Auer

Boris

Charles Winninger

Washington Dimsdale

Brian Donlevy

Kent

Allen Jenkins

Gyp Watson

Warren Hymer

Bugs Watson

Irene Hervey

Janice Tyndall

Una Merkel

Lily Belle

Billy Gilbert

Loupgerou

Samuel S. Hinds

Judge Slade

Jack Carson

Jack Tyndall

Tom Fadden

Lem Claggett

Virginia Brissac

Sophie Claggett

Edmund MacDonald

Rockwell (as Edmund Macdonald)

Lillian Yarbo

Clara

Joe King

Sheriff Keogh

Dickie Jones

Claggett Boy

Ann E. Todd

Claggett Girl

Richard Alexander

Cowboy (uncredited)

Silver Tip Baker

Barfly (uncredited)

Chief John Big Tree

Indian in Saloon (uncredited)

Billy Bletcher

Pianist (uncredited)

Buck Bucko

Barfly (uncredited)

Roy Bucko

Barfly (uncredited)

George Chesebro

Barfly (uncredited)

Dora Clement

Woman (uncredited)

Bill Cody Jr.

Townsboy Telling Wash of Destry's Arrival (uncredited)

Spade Cooley

Fiddle Player (uncredited)

Harry Cording

Creepy - Lends Tom Guns (uncredited)

Tex Driscoll

Barfly (uncredited)

Florence Dudley

Small Role (uncredited)

Lloyd Ingraham

Express Agent with Box of Rabbits (uncredited)

Marjorie Kane

Saloon Floozie (uncredited)

Cactus Mack

Musician (uncredited)

Philo McCullough

Bartender (uncredited)

Robert McKenzie

Doctor (uncredited)

Charles Murphy

Townsman (uncredited)

Betta St. John

Singing Girl in Wagon (uncredited)

William Steele

Cowboy (uncredited)

Al Taylor

Townsman (uncredited)

Harry Tenbrook

Stage Shotgun Rider

Minerva Urecal

Mrs. DeWitt (uncredited)

Leslie Vincent

(uncredited)

Dan White

Barfly (uncredited)

Blackie Whiteford

Juror (uncredited)

Duke York

Townsman (uncredited)