Millie Bobby Brown

Enola Holmes

Henry Cavill

Sherlock Holmes

Sam Claflin

Mycroft Holmes

Helena Bonham Carter

Eudoria Holmes

Louis Partridge

Lord Tewkesbury

Adeel Akhtar

Lestrade

Fiona Shaw

Miss Harrison

Frances de la Tour

The Dowager

Burn Gorman

Linthorn

Susan Wokoma

Edith

Claire Rushbrook

Mrs. Lane

David Bamber

Sir Whimbrel

Hattie Morahan

Lady Tewkesbury

Gaby French

Seamstress

Paul Copley

Station Master

Ellie Haddington

Miss Gregory

Alex Kelly

Miss Gregory II

James Duke

Footman

Connor Catchpole

Gardener

Sarah Flind

Tea Shop Assistant

Dempsey Bovell

Fleet Street Hawker

Neil Bell

Constable

Sofia Stavrinou

Young Enola

David Kirkbride

Agitator

Delroy Atkinson

Porter

Mary Roscoe

Grace Whitting

Anthony Aje

Newspaper Boy (House of Lords)

Anthony Rickman

Newspaper Boy (Fleet Street)

Tuyen Do

Boarding School Teacher

Owen Atlas

Young Sherlock Holmes (uncredited)

Jay Simpson

Conductor (uncredited)