Hilary Swank

Claire Morgan

Michelle Pfeiffer

Ingrid

Zac Efron

Paul

Robert De Niro

Stan Harris

Halle Berry

Nurse Aimee

Jessica Biel

Tess Byrne

Seth Meyers

Griffin Byrne

Til Schweiger

James Schwab

Katherine Heigl

Laura

Jon Bon Jovi

Jensen

Sofía Vergara

Ava

Ashton Kutcher

Randy

Lea Michele

Elise

Sarah Jessica Parker

Kim

Abigail Breslin

Hailey

Josh Duhamel

Sam

Ludacris

Brendan

Héctor Elizondo

Kominsky

Carla Gugino

Spiritual Dr. Morriset

Cary Elwes

Stan's Doctor

Alyssa Milano

Nurse Mindy

Sarah Paulson

Grace Schwab

Russell Peters

Chef Sunil

Jake T. Austin

Seth

Larry Miller

Harley

Charlotte Marshall-Fricker

Caring Teenage Girl

Fiona Choi

Balinese Woman

Mary Marguerite Keane

Pet Adoption Clerk

Michael Mandell

Murray

Common

Soldier

Barbara Marshall

Head Nurse Helen

Amber Bela Muse

Nurse Risa

Peter Allen Vogt

Male Nurse

Ross Ryman

Pedicab Driver

Kal Parekh

Male Obstetrician

Serena Poon

Chef Ming

Jim Belushi

Building Super

Mara Davi

Mika

Cassidy Reiff

Piper

Nat Wolff

Walter

Katherine McNamara

Lily Bowman

Beth Kennedy

Piper's Mom

Joey McIntyre

Groom Rory

Jackie Seiden

Bride Trish

Sean O'Bryan

Pastor Edwin

Jack McGee

Grandpa Jed

Yeardley Smith

Maude

Benjamin McGowan

Logan

Juliette Angelo

Sadie

Penny Marshall

Penny Marshall

Drena De Niro

Ahern Waitress

Christine Lakin

Waitress Alyssa

Sandra Taylor

Patty

Shea Curry

Wendy

Earl Rose

Pianist

Amar'e Stoudemire

Party Dancer

Cherry Jones

Mrs Rose Ahern

Matthew Walker

Engineer Douglas

Rob Nagle

Officer Nolan

David Valcin

Reporter Murphy

Patrick Collins

Reporter Fadda

Tom Hines

Announcer Brady Finley

Emily Moss Wilson

Crazy Jensen Fan

Stevvi Alexander

Backup Singer

Nicole Dupre Sobchack

Kissing Reveler #1

Anna Kulinova

Kissing Reveler #2

Ryan Seacrest

Ryan Seacrest

John Lithgow

Jonathan Cox (uncredited)

Matthew Broderick

Mr. Buellerton (uncredited)

Michael Bloomberg

Michael Bloomberg (uncredited)